The Integrin Alpha V pipeline drugs market research report outlays comprehensive information on the Integrin Alpha V targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Integrin Alpha V pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Ophthalmology, Respiratory, and Musculoskeletal Disorders which include the indications Solid Tumor, Breast Cancer, Diabetic Macular Edema, Wet (Neovascular / Exudative) Macular Degeneration, Idiopathic Pulmonary Fibrosis, Fibrosis, and Osteoporosis. It also reviews key players involved in Integrin Alpha V targeted therapeutics development with respective active and dormant or discontinued products.
The Integrin Alpha V pipeline targets constitutes close to 41 molecules. Out of which, approximately 31 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 4, 6, 2, 16, and 2 respectively. Similarly, the universities portfolio in Phase I, Preclinical, and Discovery comprises 2, 7, and 1 molecule.
Integrin Alpha V overview
Integrin alpha-V is a protein encoded by the ITGAV gene. Alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin regulate angiogenesis and cancer progression.
For a complete picture of Integrin Alpha V’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
