The Integrin Alpha M pipeline drugs market research report outlays comprehensive information on the Integrin Alpha M targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Integrin Alpha M pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Immunology, Oncology, Cardiovascular, and Central Nervous System which include the indications Inflammation, Lupus Nephritis, Non-Small Cell Lung Cancer, Follicular Lymphoma, Vascular Injury, Thrombosis, and Multiple Sclerosis. It also reviews key players involved in Integrin Alpha M targeted therapeutics development with respective active and dormant or discontinued products.
The Integrin Alpha M pipeline targets constitutes close to six molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, and Preclinical stages are 1, 2, and 2 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Integrin Alpha M overview
Integrin alpha M, also referred to as ITGAM, is a cell surface receptor protein classified within the integrin family. Integrin ITGAM/ITGB2 is involved in a variety of adhesive interactions among immune cells like monocytes, macrophages, and granulocytes. It also plays a role in facilitating the internalization of particles and pathogens coated with complement components. Notably, it shares identical features with CR-3, serving as the receptor for the iC3b fragment of the third complement component. It is likely to recognize the R-G-D peptide within C3b. Additionally, Integrin ITGAM/ITGB2 acts as a receptor for fibrinogen, factor X, and ICAM1, with the ability to recognize specific P1 and P2 peptides in the fibrinogen gamma chain. Furthermore, it contributes to the regulation of neutrophil migration, guiding these white blood cells to sites of infection or inflammation.
For a complete picture of Integrin Alpha M’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
