The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 136,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Cell & gene therapy in pharma: recombinant viral vectors. Buy the report here.
According to GlobalData’s Technology Foresights, which uses over 730,000 patents to analyze innovation intensity for the pharmaceutical industry, there are 80+ innovation areas that will shape the future of the industry.
Recombinant viral vectors is a key innovation area in the cell & gene therapy
Recombinant viral vectors are efficient vehicles with the ability to deliver a gene of choice to target cells/tissue. Viral vectors are derived from different viruses and as such are characterized by different features. These vectors play a fundamental role in molecular biology research and are applicable in the field of gene therapy and vaccine development.
GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 375+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of recombinant viral vector-based medicinal preparations.
Key players in recombinant viral vectors – a disruptive innovation in the pharmaceutical industry
‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.
‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.
Patent volumes related to recombinant viral vectors
Company | Total patents (2021 - 2023) | Premium intelligence on the world's largest companies |
C. H. Boehringer Sohn AG & Co KG | 506 | Unlock Company Profile |
Bavarian Nordic AS | 365 | Unlock Company Profile |
Merck & Co Inc | 306 | Unlock Company Profile |
Johnson & Johnson | 298 | Unlock Company Profile |
GSK plc | 241 | Unlock Company Profile |
Centre National de la Recherche Scientifique | 185 | Unlock Company Profile |
Etubics Corp | 129 | Unlock Company Profile |
Pfizer Inc | 116 | Unlock Company Profile |
Hookipa Pharma Inc | 86 | Unlock Company Profile |
AlphaVax Inc | 85 | Unlock Company Profile |
Precigen Inc | 75 | Unlock Company Profile |
CareGroup Inc | 69 | Unlock Company Profile |
Compagnie Merieux Alliance SAS | 67 | Unlock Company Profile |
Sanofi | 61 | Unlock Company Profile |
Otsuka Holdings Co Ltd | 60 | Unlock Company Profile |
NantWorks LLC | 54 | Unlock Company Profile |
Nant Holdings Ip, LLC | 50 | Unlock Company Profile |
Altimmune Inc | 49 | Unlock Company Profile |
Helmholtz Association of German Research Centres | 46 | Unlock Company Profile |
Theravectys SA | 45 | Unlock Company Profile |
Akamis Bio Ltd | 41 | Unlock Company Profile |
Novartis AG | 40 | Unlock Company Profile |
ViroNovative BV | 36 | Unlock Company Profile |
Genelux Corp | 34 | Unlock Company Profile |
Zoetis Inc | 33 | Unlock Company Profile |
Gritstone Bio Inc | 33 | Unlock Company Profile |
Vaxart Inc | 32 | Unlock Company Profile |
Gilead Sciences Inc | 31 | Unlock Company Profile |
Emergent BioSolutions Inc | 31 | Unlock Company Profile |
Erasmus MC | 31 | Unlock Company Profile |
Baxter International Inc | 31 | Unlock Company Profile |
Intervet | 27 | Unlock Company Profile |
International AIDS Vaccine Initiative | 26 | Unlock Company Profile |
Memorial Sloan Kettering Cancer Center | 25 | Unlock Company Profile |
Nouscom AG | 25 | Unlock Company Profile |
Takeda Pharmaceutical Co Ltd | 24 | Unlock Company Profile |
Mayo Clinic | 24 | Unlock Company Profile |
The United States Of America | 23 | Unlock Company Profile |
GeoVax Labs Inc | 22 | Unlock Company Profile |
City of Hope | 22 | Unlock Company Profile |
NEW HOPE, CITY OF | 21 | Unlock Company Profile |
Panacea Biotec Ltd | 21 | Unlock Company Profile |
RegenxBio Inc | 20 | Unlock Company Profile |
U.S. Department of Defence | 19 | Unlock Company Profile |
CanSino Biologics Inc | 18 | Unlock Company Profile |
AMVAC C.V. | 18 | Unlock Company Profile |
American Gene Technologies International Inc | 17 | Unlock Company Profile |
US Government | 17 | Unlock Company Profile |
Profectus BioSciences Inc | 16 | Unlock Company Profile |
I'rom Group Co Ltd | 16 | Unlock Company Profile |
Source: GlobalData Patent Analytics
Merck is one of the leading patent filers in recombinant viral vector-based medicinal preparations. It is a biopharmaceutical company focused on the discovery, development, manufacturing and marketing of prescription medicines, biologic therapies, vaccines, and animal health products. V-184, Lassa fever vaccine, LV-305, and MV-ZIKA are some of the recombinant vector vaccines, which are in clinical stages of development by Merck. Other leading patent filers in recombinant viral vectors include C. H. Boehringer Sohn and Bavarian Nordic.
In terms of application diversity, Mayo Clinic is the top company, followed by Mount Sinai Health and Erasmus MC.
By means of geographic reach, Vaxart holds the top position, Otsuka and American Gene Technologies are in second and third positions, respectively.
To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.
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