The Indoleamine 2,3 Dioxygenase 1 pipeline drugs market research report outlays comprehensive information on the Indoleamine 2,3 Dioxygenase 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Indoleamine 2,3 Dioxygenase 1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Metabolic Disorders, and Dermatology which include the indications Solid Tumor, Oncology, Psoriasis, Rheumatoid Arthritis, Type 1 Diabetes (Juvenile Diabetes), and Alopecia. It also reviews key players involved in Indoleamine 2,3 Dioxygenase 1 targeted therapeutics development with respective active and dormant or discontinued products.
The Indoleamine 2,3 Dioxygenase 1 pipeline targets constitutes close to 29 molecules. Out of which, approximately 24 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 2, 4, 5, 10, and 3 respectively. Similarly, the universities portfolio in Preclinical comprises 5 molecule.
Indoleamine 2,3 Dioxygenase 1 overview
Indoleamine-pyrrole 2, 3-dioxygenase 1 is a heme-containing enzyme encoded by the IDO1 gene. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme plays a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity.
For a complete picture of Indoleamine 2,3 Dioxygenase 1’s drug pipeline, buy the report here.
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