IK-595 is under clinical development by Ikena Oncology and currently in Phase I for Melanoma. According to GlobalData, Phase I drugs for Melanoma have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how IK-595’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
IK-595 overview
IK-595 is under development for the treatment of solid tumor, pancreatic cancer, non-small cell lung cancer, colorectal cancer, melanoma, thyroid carcinoma, nerve sheath tumors, gliomas, breast cancer, acute myeloid leukemia model. It is administered through oral route. It acts by targeting mitogen activated protein kinase kinase (MEK)-RAF complex.
Ikena Oncology overview
Ikena Oncology is a clinical-stage biotechnology company that discovers and develops novel cancer therapies. Its pipeline products include IK-930, IK-595 and IK-175. The company’s pipeline treats hippo-altered cancers, RAS (Rat Sarcoma) mutated cancers and bladder cancer. Ikena Oncology targeted program carries out in hippo and RAS (Rat Sarcoma) such as IK-930 TEAD inhibitor and IK-595: MEK-CRAF inhibition. Its immune signal targeting programs in tumor microenvironment modulation (TME) such as AHR inhibition and IK-175: AHR antagonist. The company’s program is built on robust translational research. Ikena Oncology is headquartered in Boston, Massachusetts, the US.
For a complete picture of IK-595’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
