The Histone Acetyltransferase p300 pipeline drugs market research report outlays comprehensive information on the Histone Acetyltransferase p300 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Histone Acetyltransferase p300 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Toxicology, and Undisclosed which include the indications Prostate Cancer, Breast Cancer, Autoimmune Disorders, Radiation Injury, and Unspecified. It also reviews key players involved in Histone Acetyltransferase p300 targeted therapeutics development with respective active and dormant or discontinued products.
The Histone Acetyltransferase p300 pipeline targets constitutes close to 21 molecules. Out of which, approximately 15 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 5, 1, 7, and 1 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 4, and 2 molecule.
Histone Acetyltransferase p300 overview
Histone acetyltransferase p300 (EP300) is an enzyme, that is encoded by the EP300 gene. It functions as histone acetyltransferase that regulates transcription of genes via chromatin remodeling by allowing histone proteins to wrap DNA less tightly. EP300 mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. It plays an essential role in regulating cell growth and division, prompting cells to mature and assume specialized functions, and preventing the growth of cancerous tumors.
For a complete picture of Histone Acetyltransferase p300’s drug pipeline, buy the report here.
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