The High Affinity Nerve Growth Factor Receptor pipeline drugs market research report outlays comprehensive information on the High Affinity Nerve Growth Factor Receptor targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the High Affinity Nerve Growth Factor Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Central Nervous System, Ophthalmology, and Immunology which include the indications Solid Tumor, Non-Small Cell Lung Cancer, Alzheimer’s Disease, Pain, Keratoconjunctivitis Sicca (Dry Eye), Keratitis, Inflammation, and Sicca Syndrome (Sjogren). It also reviews key players involved in High Affinity Nerve Growth Factor Receptor targeted therapeutics development with respective active and dormant or discontinued products.
The High Affinity Nerve Growth Factor Receptor pipeline targets constitutes close to 44 molecules. Out of which, approximately 42 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 4, 6, 12, 4, 12, and 3 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 1, and 1 molecule.
High Affinity Nerve Growth Factor Receptor overview
Tropomyosin receptor kinase A or high affinity nerve growth factor receptor is a protein encoded by the NTRK1 gene. High affinity receptor for NGF bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding undergoes homodimerization, autophosphorylation and activation. It phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation.
For a complete picture of High Affinity Nerve Growth Factor Receptor’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
