Harrow Health has been granted a patent for formulations and compositions targeting ocular diseases like dry eye. The composition, stored in a dropper bottle, includes various ingredients and is preservative-free. The patent also covers methods for manufacturing these ocular formulations. GlobalData’s report on Harrow Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Harrow Health, Peptide pharmacophores was a key innovation area identified from patents. Harrow Health's grant share as of April 2024 was 27%. Grant share is based on the ratio of number of grants to total number of patents.

Preservative-free ophthalmic composition for ocular diseases

Source: United States Patent and Trademark Office (USPTO). Credit: Harrow Health Inc

A recently granted patent (Publication Number: US11918603B2) discloses a unique ophthalmic composition stored in a dropper bottle that is preservative-free. The composition includes a combination of ingredients such as povidone, fully hydrolyzed polyvinyl alcohol, partially hydrolyzed polyvinyl alcohol, sodium chloride, boric acid, disodium edetate dihydrate, potassium chloride, glycerin, ethyl alcohol, lecithin, polysorbate 80, a pH adjusting agent, and water. The fully hydrolyzed polyvinyl alcohol in the composition has a specific molecular weight range of 20,000 to 200,000 daltons, ensuring its efficacy.

Furthermore, the patent outlines specific concentrations for each ingredient in the composition, ranging from povidone to polysorbate 80, ensuring the optimal balance and effectiveness of the ophthalmic solution. The composition's pH is regulated to be no more than 6.6, and its osmolality falls within the range of 200 mOsm/kg to 400 mOsm/kg. Additionally, the dropper bottle housing the composition is designed with a squeezable container and a tapered dispenser ending in a discharge aperture, providing ease of use for the consumer. The bottle has a standard volume of 10 mL, making it convenient for regular ophthalmic applications.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies