The GTPase KRas pipeline drugs market research report outlays comprehensive information on the GTPase KRas targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the GTPase KRas pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Ophthalmology, Undisclosed, and Dermatology which include the indications Solid Tumor, Non-Small Cell Lung Cancer, Macular Degeneration, Diabetic Retinopathy, Unspecified, and Actinic (Solar) Keratosis. It also reviews key players involved in GTPase KRas targeted therapeutics development with respective active and dormant or discontinued products.
The GTPase KRas pipeline targets constitutes close to 252 molecules. Out of which, approximately 234 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 3, 5, 19, 25, 8, 97, and 77 respectively. Similarly, the universities portfolio in Phase II, Phase I, Preclinical, and Discovery comprises 2, 3, 9, and 4 molecule.
GTPase KRas overview
KRAS is a GTPase encoded by the KRAS gene. It plays an important role in the regulation of cell proliferation, promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
For a complete picture of GTPase KRas’s drug pipeline, buy the report here.
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