Ginkgo Bioworks has been granted a patent for modified AAV capsid proteins and virus vectors for administering to cells or subjects in vivo. The patent claim specifies the amino acid sequence of the AAV capsid protein. GlobalData’s report on Ginkgo Bioworks gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Ginkgo Bioworks, was a key innovation area identified from patents. Ginkgo Bioworks's grant share as of May 2024 was 16%. Grant share is based on the ratio of number of grants to total number of patents.
Modified aav capsid protein for virus vectors
A recently granted patent (Publication Number: US11981914B2) discloses an adeno-associated virus (AAV) vector containing a specific AAV capsid protein with a defined amino acid sequence. This vector is designed to encapsidate a cargo nucleic acid, which may include terminal repeat sequences and heterologous nucleic acid sequences. The cargo nucleic acid can encode various molecules such as therapeutic polypeptides, immunogenic polypeptides, nucleases like Cas9, or untranslated RNAs like guide RNAs, antisense RNAs, ribozymes, or interfering RNAs.
Furthermore, the patent covers a method for introducing the cargo nucleic acid into cells using the AAV vector, as well as the production of the AAV vector itself. This involves culturing cells containing specific nucleic acid sequences, including the AAV capsid protein sequence, cargo nucleic acid, and necessary AAV replication and encapsidation sequences, to produce the AAV vector. The vector is then collected from the cultured cells for further use. The patent also includes claims related to the AAV capsid protein itself, a nucleic acid encoding it, cells containing this nucleic acid, and an expression vector with the nucleic acid sequence for the AAV capsid protein.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
