The Germ Cell Tumors drugs in development market research report provides comprehensive information on the therapeutics under development for Germ Cell Tumors, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses key aspects of the companies and drugs in development for Germ Cell Tumors. Buy the report here.

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Data Insights Germ Cell Tumors - Drugs In Development, 2024

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The report also covers the descriptive pharmacological action of the therapeutics and the latest news and press releases. Additionally, the report provides an overview of the key players involved in therapeutic development for Germ Cell Tumors and features dormant and discontinued products.

GlobalData tracks 17 drugs in development for Germ Cell Tumors by 14 companies/universities/institutes. The top development phase for Germ Cell Tumors is phase ii with ten drugs in that stage. The Germ Cell Tumors pipeline has 16 drugs in development by companies and one by universities/ institutes. Some of the companies in the Germ Cell Tumors pipeline products market are: Pharma Mar, Novartis and AstraZeneca.

The key targets in the Germ Cell Tumors pipeline products market include Tubulin, Programmed Cell Death Protein 1, and Serine/Threonine Protein Kinase B Raf.

The key mechanisms of action in the Germ Cell Tumors pipeline product include Tubulin Inhibitor with two drugs in Phase II. The Germ Cell Tumors pipeline products include 11 routes of administration with the top ROA being Intravenous and six key molecule types in the Germ Cell Tumors pipeline products market including Monoclonal Antibody, and Small Molecule.

Germ Cell Tumors overview

Germ cell tumors (GCTs), originating from primordial germ cells, exhibit diverse neoplasms primarily in gonads but also in the anterior mediastinum, pineal gland, and brain. Clinical classification distinguishes seminomas and non-seminomas, each with distinct prognoses. Seminomas typically show favorable outcomes, while non-seminomatous tumors may present with metastasis, including mixed germ cell components. Diagnosing germinoma involves imaging, serum/cerebrospinal fluid oncoprotein measurements, and histological biopsy. Germinoma boasts a favorable prognosis with over 90% 5-year survival rates, highly responsive to radiotherapy (RT) and chemotherapy (CT). Current practices favor whole ventricular irradiation over craniospinal irradiation due to reduced side effects. Platinum-based CT combinations precede low-dose ventricular irradiation, minimizing toxicity. Surgical roles are limited, mainly for diagnosis and managing obstructive hydrocephalus, with second-look surgery considered for non-responsive tumors.

For a complete picture of Germ Cell Tumors’s pipeline drug market, buy the report here.

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GlobalData’s pipeline drugs offers detailed profiles of pharmaceutical drugs in all stages of pre-clinical and clinical development, from discovery through to pre-registration. Coverage is limited to novel human medicinal drugs and biosimilars seeking market approval proprietary and is one of two primary repositories of pharmaceutical drug information offered by GlobalData through its Pharmaceutical Intelligence Center.