The Fibroblast Growth Factor Receptor 4 pipeline drugs market research report outlays comprehensive information on the Fibroblast Growth Factor Receptor 4 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Fibroblast Growth Factor Receptor 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Gastrointestinal, Metabolic Disorders, and Genito Urinary System which include the indications Hepatocellular Carcinoma, Solid Tumor, Constipation, Oral Mucositis, Type 2 Diabetes, Obesity, Benign Prostatic Hyperplasia, and Kidney Disease (Nephropathy). It also reviews key players involved in Fibroblast Growth Factor Receptor 4 targeted therapeutics development with respective active and dormant or discontinued products.
The Fibroblast Growth Factor Receptor 4 pipeline targets constitutes close to 38 molecules. Out of which, approximately 35 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 4, 5, 10, 2, 9, and 4 respectively. Similarly, the universities portfolio in Phase I, and Preclinical comprises 1, and 2 molecule.
Fibroblast Growth Factor Receptor 4 overview
Fibroblast growth factor receptor 4 is a protein encoded by the FGFR4 gene. It plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. It is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. It phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades.
For a complete picture of Fibroblast Growth Factor Receptor 4’s drug pipeline, buy the report here.
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