F. Hoffmann-La Roche had 13 patents in advanced materials during Q1 2024. Description: The patents filed by F. Hoffmann-La Roche Ltd in Q1 2024 focus on devices and methods for sequencing linear biomolecules using quantum tunneling effects, as well as forming nanopores in lipid bilayers. The devices involve nanofabricated structures with precise gap dimensions for detecting biomolecules, while the method for forming nanopores in lipid bilayers involves controlling the concentration and activity levels of pore molecules to initiate nanopore formation only when stimulated. These innovations aim to improve the accuracy and efficiency of biomolecule sequencing and analysis. GlobalData’s report on F. Hoffmann-La Roche gives a 360-degree view of the company including its patenting strategy. Buy the report here.
F. Hoffmann-La Roche grant share with advanced materials as a theme is 38% in Q1 2024. Grant share is based on the ratio of number of grants to total number of patents.
Recent Patents
Application: Design and methods for measuring analytes using nanofabricated device (Patent ID: US20240060956A1)
The patent by F. Hoffmann-La Roche Ltd. describes devices for sequencing linear biomolecules using quantum tunneling effects. These devices consist of nanofabricated structures with small gaps that can detect changes in tunneling current, voltage, or impedance when a biomolecule is present in the gap. The dimensions of the gap can be precisely controlled at the atomic scale, allowing for accurate identification of specific parts of the biomolecule. The system includes multiple devices on a single chip, each comprising electrodes, dielectric layers, and gaps tailored to the size of the biomolecules being sequenced.
The system also involves a method for sequencing multiple linear biomolecules simultaneously by applying voltages across the electrodes of each device, introducing parts of the biomolecules into the gaps, measuring the resulting tunneling current, voltage, or impedance, and identifying the specific parts of the biomolecules present. The method allows for efficient and accurate sequencing of biomolecules using quantum tunneling technology. The system's design, fabrication, and operation are optimized for integration with existing integrated circuit fabrication equipment and facilities, making it a practical and scalable solution for high-throughput biomolecule sequencing applications.
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