The Eukaryotic Translation Initiation Factor 4E pipeline drugs market research report outlays comprehensive information on the Eukaryotic Translation Initiation Factor 4E targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Eukaryotic Translation Initiation Factor 4E pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, and Gastrointestinal which include the indications Melanoma, Multiple Myeloma (Kahler Disease), Inflammation, Ulcerative Colitis, and Crohn’s Disease (Regional Enteritis). It also reviews key players involved in Eukaryotic Translation Initiation Factor 4E targeted therapeutics development with respective active and dormant or discontinued products.
The Eukaryotic Translation Initiation Factor 4E pipeline targets constitutes close to six molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, and Preclinical stages are 1, and 4 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Eukaryotic Translation Initiation Factor 4E overview
Eukaryotic translation initiation factor 4E, also known as eIF4E, is a protein that in humans is encoded by the EIF4E gene, which recognizes the 7-methylguanosine cap structure at the 5′ end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5′-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation are associated with transformation and tumorigenesis.
For a complete picture of Eukaryotic Translation Initiation Factor 4E’s drug pipeline, buy the report here.
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