ES-4000 is under clinical development by Escend Pharmaceuticals and currently in Phase I for Metastatic Breast Cancer. According to GlobalData, Phase I drugs for Metastatic Breast Cancer have an 82% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ES-4000’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
ES-4000 overview
ES-4000 is under development for the treatment of pancreatic cancer, metastatic breast cancer and melanoma. The drug candidate acts by targeting Cyclin D and C-Myc proto oncogene protein. It is administered through oral route.
Escend Pharmaceuticals overview
Escend Pharmaceuticals is developing orally bioavailable small molecules to improve treatment outcomes for patients with cancer orphan disease indications. The company is headquartered in Menlo Park, California, the US.
For a complete picture of ES-4000’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
