DFV-890 is under clinical development by Novartis and currently in Phase II for Inflammation. According to GlobalData, Phase II drugs for Inflammation have a 38% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how DFV-890’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
DFV-890 overview
DFV-890 is under development for the treatment of familial cold autoinflammatory syndrome, low risk myelodysplastic syndromes, coronary heart disease (CVD), chronic myelomonocytic leukemia, dermatological immunological diseases, inflammatory marker reduction in adult participants with coronary heart disease and elevated hscrp and osteoarthritis pain. It is administered through oral route. It acts by targeting NLRP3.
It was under development for the treatment of non-alcoholic steatohepatitis (NASH), inflammatory bowel disease, liver, atherosclerosis and Coronavirus disease 2019 (COVID-19) pneumonia.
Novartis overview
Novartis is a healthcare company that focuses on the discovery, development, manufacture and marketing of prescription and generic pharmaceutical products and eye care products. It provides drugs for the treatment of cancer, cardiovascular diseases, dermatological conditions, neurological disorders, ophthalmic and respiratory diseases, hematologic diseases, solid tumors, immune disorders, and infections, among others. Novartis conducts research in various disease areas through the BioMedical Research division. The company operates through a network of subsidiaries and offices across the Americas, Europe, the Middle East, Africa and Asia-Pacific. Novartis is headquartered in Basel, Switzerland.
For a complete picture of DFV-890’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
