Delpazolid is under clinical development by LigaChem Biosciences and currently in Phase II for Mycobacterium Infections. According to GlobalData, Phase II drugs for Mycobacterium Infections have a 57% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Delpazolid’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Delpazolid overview

Delpazolid (LCB-010371) is under development for the treatment of refractory Mycobacterium abscessus Complex Pulmonary disease (MABC), gram-positive bacterial infections including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci infections, Streptococcus pneumoniae infections, multidrug-resistant tuberculosis infections and pulmonary tuberculosis. It is a next-generation oxazolidinone antibiotic administered through oral and intravenous route. It acts by targeting 23s ribosomal RNA.

LigaChem Biosciences overview

LigaChem Biosciences (LCB) is a biotechnology company that discovers and develops novel therapeutics for infectious diseases, oncology, and immuno-oncology indications. Its pipeline products include LCB14, LCB84, LCB71, LCB73, LCB97, LCB02A, LCB41A, LCB67, LCB69, LCB85, LCB20A, LCB42A, LCB19A, LCB91, LCB06A, LCB18A, LCB36A and others. The company products are used in the therapeutic areas of antibiotics, anti-fibrotics, oncology and antibody-drug conjugate (ADC) platform technology. It operates in China. LCB is headquartered in Daejeon, South Korea.

For a complete picture of Delpazolid’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 12 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.