Dactolisib tosylate + everolimus is under clinical development by Adicet Bio and currently in Phase II for Respiratory Tract Infections. According to GlobalData, Phase II drugs for Respiratory Tract Infections have a 67% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Dactolisib tosylate + everolimus’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Dactolisib tosylate + everolimus overview
Dactolisib tosylate in combination with everolimus is under development for the treatment of aging-related immunosenescence, respiratory tract infection, Parkinson's disease aging-related organ failure/dysfunction, TORC1 / autophagy-related diseases, infections. The drug candidate acts by targeting mTORC1. It was also under development for urinary tract disorders.
It was under development for the treatment diastolic heart failure.
Adicet Bio overview
Adicet Bio is a clinical-stage biotechnology company. It primarily focuses on the discovery and development of allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. The company’s product candidate is ADI-001, an investigational allogeneic gamma delta CAR T cell therapy that targets B-cells via an anti-CD20 CAR. Adicet’s products are designed for patients suffering from autoimmune diseases, solid tumors, and hematological malignancies. It also develops ADI-002, used for the treatment of various solid tumors; and ADI-925, a novel engineered CAd gamma delta T cell product candidate targeting tumor stress ligands. The company operates in the US. Adicet Bio is headquartered in Boston, Massachusetts, the US.
For a complete picture of Dactolisib tosylate + everolimus’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
