CUSP-06 is under clinical development by OnCusp Therapeutics and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 69% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how CUSP-06’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
CUSP-06 overview
CUSP-06 (AMT-707) is under development for the treatment of solid tumors, kidney (renal), ovarian cancer, renal cell carcinoma and cholangiocarcinoma. It is administered by parenteral and intravenous route.The drug candidate is a antibody drug conjugate composed of a proprietary antibody with high CDH6 binding affinity, a protease cleavable linker, and an exatecan payload (a potent and clinically validated topoisomerase-1 inhibitor) and is being developed based on MabArrayTM technology. It acts by targeting tumor cells expressing cadherin 6 (CDH6) and acts as topoisomerase-1 inhibitor.
OnCusp Therapeutics overview
OnCusp Therapeutics is a biopharmaceutical company developing oncology therapeutics for the treatment of cancer patients. The company is headquartered in New York City, New York, the US.
For a complete picture of CUSP-06’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
