CRN-04894 is under clinical development by Crinetics Pharmaceuticals and currently in Phase II for Congenital Adrenal Hyperplasia (Adrenogenital Syndrome). According to GlobalData, Phase II drugs for Congenital Adrenal Hyperplasia (Adrenogenital Syndrome) does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the CRN-04894 LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
CRN-04894 overview
CRN-04894 is under development for the treatment of Cushing disease, congenital adrenal hyperplasia (CAH) and ectopic ACTH syndrome. The drug candidate is administered through oral route and acts by targeting adrenal corticotropic hormone (ACTH) receptor.
Crinetics Pharmaceuticals overview
Crinetics Pharmaceuticals is a clinical-stage pharmaceutical company that discovers, develops and commercializes novel therapeutics for endocrine diseases and endocrine-related tumors. The company’s pipeline products include paltusotine an oral somatostatin receptor type 2 (SST2) agonist that treats acromegaly and carcinoid syndrome; and CRN04894 an ACTH agonist that targets Cushing’s disease and congenital adrenal hyperplasia (CAH); PTH antagonist, SST3 agonist, SST5 agonist and TSH antagonist for hyperparathyroidism, polycystic kidney disease hyperinsulinism and graves’ disease; oral GLP-1 nonpeptide and oral GIP nonpeptide target diabetes and obesity. The company operates through its subsidiary in Australia. Crinetics Pharmaceuticals is headquartered in San Diego, California, the US.
For a complete picture of CRN-04894’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
