CLN-617 is under clinical development by Cullinan Therapeutics and currently in Phase I for Metastatic Melanoma. According to GlobalData, Phase I drugs for Metastatic Melanoma have an 81% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how CLN-617’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
CLN-617 overview
CLN-617 is under development for the treatment of solid tumors including metastatic melanoma and head and neck cancer squamous cell carcinoma. The therapeutic candidate is a next-generation cytokine fusion protein comprises of interleukin-12 (IL-12) and interleukin-2 (IL-2), along with a collagen-binding domain which is administered by intratumoral route. It is being developed based on the AMBER technology.
Cullinan Therapeutics overview
Cullinan Therapeutics, formerly Cullinan Oncology Inc, is clinical-stage biotechnology company. It focuses on the discovery and development of oncology therapies. Its product pipeline includes CLN-081 for the treatment of non-small cell lung cancer; CLN-619 against pan-cancer; and CLN-049 to treat relapsed and refractory acute myelogenous leukemia (AML), and myelodysplastic syndrome (MDS). Cullinan Therapeutic;s pipeline also includes drug programs such as CLN-418 for multiple solid tumors; CLN-978 to treat B-cell non-Hodgkin lymphomas; and CLN-617 for treatment of pan-cancer. The company also provides various patient support programs. Cullinan Therapeutics is headquartered in Cambridge, Massachusetts, the US.
For a complete picture of CLN-617’s drug-specific PTSR and LoA scores, buy the report here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.