CK-0045 is under clinical development by CytoKi Pharma and currently in Phase II for Obesity. According to GlobalData, Phase II drugs for Obesity have a 29% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how CK-0045’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

CK-0045 overview

CK-0045 is under development for the treatment of epithelial injury in inflammatory bowel disease, type 2 diabetes and obesity. It comprises of an engineered, long-acting lipidated IL-22. It targets interleukin 22 receptor (IL22R) and is being developed based on lipidation technology. It is administered through subcutaneous route.

CytoKi Pharma overview

CytoKi Pharma is a clinical-stage biotechnology company. It develops medicines to treat metabolic diseases and conditions characterized by epithelial injury. The company’s activities involve harnessing the innate biology of Interleukin-22 (IL-22) to address these diseases. Its lead product, CK-0045, is a long-acting IL-22 analog currently undergoing clinical evaluation. Cytoki Pharma products are aimed at addressing obesity, type 2 diabetes and inflammatory bowel disease. The company’s products are designed for use in the healthcare industry for patients suffering from the aforementioned conditions. Cytoki Pharma is headquartered in Søborg, Denmark.

For a complete picture of CK-0045’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 12 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.