The Caspase 9 pipeline drugs market research report outlays comprehensive information on the Caspase 9 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Caspase 9 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Ophthalmology, Central Nervous System, and Dermatology which include the indications Oncology, Prostate Cancer, Diabetic Retinopathy, Age Related Macular Degeneration, Alzheimer’s Disease, Parkinson’s Disease, Actinic (Solar) Keratosis, and Atopic Dermatitis (Atopic Eczema). It also reviews key players involved in Caspase 9 targeted therapeutics development with respective active and dormant or discontinued products.
The Caspase 9 pipeline targets constitutes close to eight molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Filing rejected/ Withdrawn, and Preclinical stages are 1, and 4 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 1, and 2 molecule.
Caspase 9 overview
Caspase-9 is an initiator caspase encoded by the CASP9 gene. Binding of caspase-9 to Apaf-1 leads to activation of the protease which cleaves and activates caspase-3. It is involved in the activation cascade of caspases responsible for apoptosis execution. It promotes DNA damage-induced apoptosis in an ABL1/c-Abl-dependent manner.
For a complete picture of Caspase 9’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
