Carfostin is under clinical development by Asklepios BioPharmaceutical and currently in Phase II for Congestive Heart Failure (Heart Failure). According to GlobalData, Phase II drugs for Congestive Heart Failure (Heart Failure) have a 46% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Carfostin’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Carfostin overview
Carfostin (BNP-CHF) is under development for the treatment of advanced stage III/IV chronic heart failure and chronic non-ischemic cardiomyopathy. The drug candidate is a protein and cellular therapy based recombinant adeno-associated virus (rAAV) biological nanoparticle. The drug candidate is based on Biological Nano Particles (BNP) technology and Self-Complementary Vector technology. It targets protein phosphatase 1.
Asklepios BioPharmaceutical overview
Asklepios BioPharmaceutical (AskBio), a subsidiary of Bayer AG, is a clinical-stage gene therapy company. It focuses on advancing genetic technology and developing life-saving adeno-associated virus (AAV) gene therapies. The company’s main activities include research and development of gene therapies targeting a range of disorders, including central nervous system, neuromuscular, metabolic, and cardiovascular diseases. AskBio’s product pipeline includes therapies for the treatment of neuromuscular, central nervous system, heart-related diseases including pompe, limb-girdle 2i, huntington’s, multiple system atrophy, parkinson’s, and congestive heart failure (nanocor). Its gene therapy solutions are utilized by patients and healthcare providers to address genetic disorders, with applications spanning various medical fields. The company operates in the US, Scotland, Germany, Spain, and France. AskBio is headquartered in Research Triangle Park, North Carolina, the US.
For a complete picture of Carfostin’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
