The Calcineurin pipeline drugs market research report outlays comprehensive information on the Calcineurin targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Calcineurin pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Ophthalmology, Immunology, Respiratory, and Dermatology which include the indications Keratoconjunctivitis Sicca (Dry Eye), Unspecified Ophthalmological Disorders, Transplant Rejection, Corneal Graft Rejection, Asthma, Acute Respiratory Distress Syndrome, Wounds, and Keloids. It also reviews key players involved in Calcineurin targeted therapeutics development with respective active and dormant or discontinued products.
The Calcineurin pipeline targets constitutes close to 36 molecules. Out of which, approximately 30 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 2, 1, 5, 11, 1, 7, and 2 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 4, and 2 molecule.
Calcineurin overview
Calcineurin is a ubiquitous enzyme that plays a critical role in various cellular processes, including T cell activation, immune response, muscle contraction, and learning and memory. It is a heterodimeric protein composed of a catalytic subunit, calcineurin A (PPP3CA), and a regulatory subunit, calcineurin B (PPP3R1). Calcineurin is activated by calcium and calmodulin, and also dephosphorylates specific serine and threonine residues on target proteins.
For a complete picture of Calcineurin’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
