Bukwang Pharmaceutical has patented a pharmaceutical composition for managing OFF-time episodes in Parkinson’s disease patients. The multi-particulate oral dosage form includes mini-tablets with specific compositions to ensure controlled release of levodopa. GlobalData’s report on Bukwang Pharmaceutical gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Bukwang Pharmaceutical, Nanoparticle drug conjugates was a key innovation area identified from patents. Bukwang Pharmaceutical's grant share as of May 2024 was 54%. Grant share is based on the ratio of number of grants to total number of patents.
Pulsatile release pharmaceutical composition for parkinson's disease management
A recently granted patent (Publication Number: US11975104B2) discloses a multi-particulate pharmaceutical dosage form designed for oral administration. The dosage form consists of a plurality of first film-coated mini-tablets, each containing a swellable and soluble core comprising levodopa and a semi-permeable film-coating. The core composition includes specific percentages of levodopa, sodium starch glycolate, microcrystalline cellulose, pregelatinized starch, and magnesium stearate, with the mini-tablets having a diameter less than or equal to 3 mm.
Furthermore, the patent claims specify the total amount of levodopa and carbidopa in the dosage form, the individual dosage of each mini-tablet, and the form in which the dosage form can be presented. The film-coating composition, compression of the mini-tablets, and the specific percentages of sodium starch glycolate in the core are also detailed in the claims. The film-coating of each mini-tablet is described to consist of ethylcellulose and HPMC in specific proportions, highlighting the precise formulation and manufacturing process of the pharmaceutical dosage form.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
