BSI-04702 is under clinical development by OBI Pharma and currently in Phase II for Non-Small Cell Lung Cancer. According to GlobalData, Phase II drugs for Non-Small Cell Lung Cancer have a 38% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how BSI-04702’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
BSI-04702 overview
BSI-04702 (OBI-992) is under development for the treatment of solid tumors, including non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), and gastric cancer (GC). It is administered through parenteral route. The therapeutic candidate comprises of antibody targeting tumor associated calcium signal transducer 2 (Trop 2) with the topoisomerase I (TOP1) payload. It is being developed based on SynTracer HT (high throughput) endocytosis and GlycOBI ADC platform.
OBI Pharma overview
OBI Pharma is a biopharmaceutical company that develops therapies for the treatment of cancer and infectious diseases. The company’s pipeline products include adagloxad simolenin, an active immunotherapy which is intended for the treatment of metastatic breast cancer and OBI-833, a cancer vaccine for epithelial cancers other than breast and ovarian cancer. It also develops active immunotherapies intended for the treatment of various lung, prostate, pancreatic, stomach and ovarian cancers. The company has collaboration with research institutes including cancer centers to enhance its pipeline products. It operates in the US, Taiwan, Hong Kong, Australia and China. OBI Pharma is headquartered in Taipei City, Taipei, Taiwan.
For a complete picture of BSI-04702’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
