BOS-580 is under clinical development by Boston Pharmaceuticals and currently in Phase II for Metabolic Dysfunction-Associated Steatohepatitis (MASH). According to GlobalData, Phase II drugs for Metabolic Dysfunction-Associated Steatohepatitis (MASH) have a 25% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how BOS-580’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
BOS-580 overview
BOS-580 is under development for the treatment of non-alcoholic steatohepatitis (NASH). It is administered by subcutaneous route. It is a genetically engineered variant of human fibroblast growth factor 21 (FGF21). It acts by targeting FGFR1c, FGFR3c and KLB. The drug candidate was also under development for obesity.
Boston Pharmaceuticals overview
Boston Pharmaceuticals (Boston Pharma) is a clinical-stage biopharmaceutical company. It develops highly engineered targeted therapies for serious liver diseases. The company’s pipeline products include BOS-580 an investigational fusion protein based on human IgG and FGF21 treats metabolic dysfunction-associated steatohepatitis (MASH); BOS-342 is an investigational bispecific antibody directed against glypican-3 (GPC3) and 4-1BB (CD137) bispecific antibody that targets hepatocellular carcinoma (HC). Boston Pharma is headquartered in Cambridge, Massachusetts, the US.
For a complete picture of BOS-580’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
