Bisantrene is under clinical development by Race Oncology and currently in Phase II for Relapsed Acute Myeloid Leukemia. According to GlobalData, Phase II drugs for Relapsed Acute Myeloid Leukemia have a 20% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Bisantrene’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Bisantrene overview
Bisantrene hydrochloride (UPI-928) is under development for the treatment of adult and pediatric relapsed and refractory acute myelogenous leukemia, permanent heart damage caused by the chemotherapeutic anthracycline doxorubicin, breast cancer, ovarian cancer, multiple myeloma. The drug candidate is a small molecule anthracene derivative. It acts by targeting FTO. It is administered through intravenous route.
It was also under development for myelodysplastic syndrome, CMML, relapsed and refractory acute myeloid leukemia.
Race Oncology overview
Race Oncology is a clinical-stage biopharmaceutical company that develops cancer treatment drugs. The company’s lead candidate RC220 bisantrene addresses treatments across multiple oncology indications, with a clinical focus on anthracycline combinations to protect patient’s hearts from the permanent damage caused by chemotherapy while providing enhanced anticancer activity in a range of solid tumors. The company’s product candidate acts as an anthracycline-like chemotherapeutic causing less cardiotoxicity (heart damage) in cancer patients. Race Oncology is headquartered in Sydney, New South Wales, Australia.
For a complete picture of Bisantrene’s drug-specific PTSR and LoA scores, buy the report here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.
GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
