BHV-7000 is a small molecule commercialized by Biohaven, with a leading Phase III program in Generalized Seizures;Partial Seizure. According to Globaldata, it is involved in 11 clinical trials, of which 1 was completed, and 10 are ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of BHV-7000’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for BHV-7000 is expected to reach an annual total of $105 mn by 2035 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
BHV-7000 Overview
BHV-7000 is under development for the treatment of neonatal encephalopathy (KCNQ2-EE), neuropathic pain, partial seizures (Adult focal epilepsy/refractory focal onset epilepsy), generalized seizures with generalized tonic-clonic seizures and mood disorders such as major depressive disorder, bipolar disorder. The drug candidates acts by targeting potassium channels Kv7.2/7.3 and are developed based on ion channel discovery platform.
It was also under development for tinnitus.
Biohaven Overview
Biohaven formerly Biohaven Research, is biopharmaceutical company discovering, developing, and commercializing novel therapies for the treatment of neurological and neuropsychiatric diseases. Biohaven is headquartered in Tortola, British Virgin Islands.
The operating loss of the company was US$436.1 million in FY2023, compared to an operating loss of US$567.9 million in FY2022. The net loss of the company was US$408.2 million in FY2023, compared to a net loss of US$570.3 million in FY2022.
For a complete picture of BHV-7000’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
