Azeliragon is under clinical development by Cantex Pharmaceuticals and currently in Phase III for Coronavirus Disease 2019 (COVID-19). According to GlobalData, Phase III drugs for Coronavirus Disease 2019 (COVID-19) have a 13% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Azeliragon’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Azeliragon overview
Azeliragon is under development for the treatment of hospitalized patients with severe COVID-19, cancer-treatment related cognitive decline, chronic obstructive pulmonary disease (COPD) and steroid refractory asthma, pneumonia, metastatic pancreatic cancer, glioblastoma multiforme, gliosarcoma, breast cancer, brain metastasis and breast cancers. The drug candidate is administered through oral route and acts by targeting RAGE (receptor for advanced glycation endproducts). The drug is developed based on the TTP translational technology. It was under development for the treatment of Alzheimer’s disease (dementia with diabetes) and diabetic nephropathy, triple-negative breast cancer (TNBC).
Cantex Pharmaceuticals overview
Cantex Pharmaceuticals is a clinical-stage pharmaceutical company focused on developing novel, well-tolerated, oral treatments for cancer and other serious illnesses. The company develops Azeliragon which is a small molecule antagonist of the receptor for advanced glycation endproducts (RAGE). It treats glioblastoma, brain metastases, pancreatic cancer, breast cancer, and the prevention of acute kidney injury in hospitalized pneumonia patients. The company offers its products across the US. Cantex Pharmaceuticals is headquartered in Weston, Florida, the US
For a complete picture of Azeliragon’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
