The ATP Citrate Synthase pipeline drugs market research report outlays comprehensive information on the ATP Citrate Synthase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the ATP Citrate Synthase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Metabolic Disorders, Gastrointestinal, Oncology, and Genito Urinary System which include the indications Hyperlipidemia, Hypercholesterolemia, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Hepatocellular Carcinoma, Unspecified Cancer, and Kidney Disease (Nephropathy). It also reviews key players involved in ATP Citrate Synthase targeted therapeutics development with respective active and dormant or discontinued products.
The ATP Citrate Synthase pipeline targets constitutes close to five molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, and Preclinical stages are 1, 1, 1, and 2 respectively.
ATP Citrate Synthase overview
ATP Citrate Synthase, or ATP Citrate Lyase (ACLY), is an essential enzyme involved in cellular metabolism, particularly in the generation of acetyl-coenzyme A (acetyl-CoA). This enzyme catalyzes the conversion of citrate and coenzyme A (CoA) into acetyl-CoA and oxaloacetate in the cytoplasm. This reaction is a pivotal step in the cytosolic production of acetyl-CoA, a critical precursor for fatty acid and cholesterol biosynthesis. The ATP Citrate Synthase-mediated production of acetyl-CoA has significant implications for cellular processes such as lipogenesis, where acetyl-CoA serves as a central building block. Beyond its role in lipid synthesis, ATP Citrate Synthase has been implicated in supporting cancer cell proliferation, as cancer cells often exhibit increased demands for lipids to support their rapid growth.
For a complete picture of ATP Citrate Synthase’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
