Assembly Biosciences. has been granted a patent for 5-membered heteroaryl carboxamide compounds that disrupt HBV core protein assembly. The patent includes pharmaceutical compositions and methods for treating Hepatitis B infection, along with a specific method for synthesizing a compound referenced as (VI-5). GlobalData’s report on Assembly Biosciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Assembly Biosciences, Cancer treatment biomarkers was a key innovation area identified from patents. Assembly Biosciences's grant share as of June 2024 was 25%. Grant share is based on the ratio of number of grants to total number of patents.

Heteroaryl carboxamide compounds for treating hepatitis b

Source: United States Patent and Trademark Office (USPTO). Credit: Assembly Biosciences Inc

The granted patent US12030869B2 outlines a method for synthesizing a specific compound referred to as compound (VI-5). The claims detail various aspects of the synthesis process, emphasizing the structural characteristics of the compound. Claim 1 establishes the foundational method for the synthesis, while subsequent claims refine the parameters by specifying the substituents on the aromatic ring (Ar) and the alkyl group (R) involved in the compound's structure.

In particular, claim 2 specifies that the aromatic group (Ar) is a phenyl ring that is substituted with both chloro and fluoro groups. Claim 4 further narrows the focus by indicating that the alkyl group (R) is methyl. The claims collectively suggest a targeted approach to synthesizing compound (VI-5), highlighting the importance of specific chemical modifications in achieving the desired compound structure. The patent thus provides a clear framework for the synthesis of this compound, which may have implications for various applications in chemical research and development.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies