Amgen has patented a method using Patent Blue dye or AMG Blue dye to determine the suitability of spectrophotometers for measuring protein concentration. By measuring absorbance at specific wavelengths, the method ensures accurate results. GlobalData’s report on Amgen gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Amgen, NSAID cancer drugs was a key innovation area identified from patents. Amgen's grant share as of May 2024 was 39%. Grant share is based on the ratio of number of grants to total number of patents.
Method for determining spectrophotometer suitability for protein concentration measurement
A recently granted patent (Publication Number: US12000775B2) outlines a method for determining the suitability of a variable-length spectrophotometer or fixed path length spectrophotometer in measuring protein concentration in a protein sample. The method involves measuring the absorbance of Patent Blue dye (PBD) or AMG Blue Dye (ABD) at specific wavelengths, including 280 nm, and subsequent wavelengths chosen from a set of options. The spectrophotometer is deemed suitable if the absorbance readings fall within a specified range compared to values provided in a certificate of analysis for the dyes. Additionally, the method includes multiple measurements before and after determining protein concentration to ensure accuracy.
Furthermore, the patent covers the analysis of various therapeutic proteins, including antibodies and derivatives, using the specified spectrophotometers. The method involves measuring absorbance at specific wavelengths and comparing the results to predetermined values to assess the instrument's suitability for protein concentration determination. The patent also mentions the use of a SoloVPE spectrophotometer for these measurements. Overall, the patent provides a detailed and structured approach to evaluating spectrophotometers for protein concentration analysis, particularly focusing on the absorbance of specific dyes at defined wavelengths to ensure accuracy and reliability in the process.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
