Acura Pharmaceuticals has been granted a patent for an abuse deterrent pharmaceutical composition. The composition includes a pharmaceutically active ingredient, an acid soluble ingredient, and a buffering ingredient to retard release of the active ingredient when ingested in excess. GlobalData’s report on Acura Pharmaceuticals gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Acura Pharmaceuticals, Nanoparticle drug conjugates was a key innovation area identified from patents. Acura Pharmaceuticals's grant share as of February 2024 was 86%. Grant share is based on the ratio of number of grants to total number of patents.
Abuse deterrent pharmaceutical composition with delayed release mechanism
A newly granted patent (Publication Number: US11857629B2) discloses an abuse-deterrent pharmaceutical composition designed to prevent misuse or abuse of drugs. The composition includes a pharmaceutically active ingredient, an acid-soluble ingredient, and a buffering ingredient. The buffering ingredient plays a crucial role in suppressing the peak plasma concentration (Cmax) of the active ingredient when the composition is ingested in excess of the therapeutic dosage, thereby deterring abuse.
Furthermore, the buffering ingredient also extends the time (Tmax) taken for the peak plasma concentration (Cmax) of the active ingredient to be reached when ingested in excess of the therapeutic dosage. This delayed release mechanism aims to prevent rapid drug absorption and potential abuse. The patent emphasizes the importance of the buffering ingredient in increasing gastric pH to above 4 when the composition is ingested in excessive amounts, further contributing to the abuse-deterrent properties of the pharmaceutical composition.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
