A. Menarini Industrie Farmaceutiche Riunite has patented a method and apparatus for reducing the volume of a sample, particularly a liquid component. The process involves accelerating a container to facilitate the outflow of liquid through an opening, while retaining a defined volume inside. GlobalData’s report on A. Menarini Industrie Farmaceutiche Riunite gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on A. Menarini Industrie Farmaceutiche Riunite, Cancer treatment biomarkers was a key innovation area identified from patents. A. Menarini Industrie Farmaceutiche Riunite's grant share as of June 2024 was 53%. Grant share is based on the ratio of number of grants to total number of patents.

Method for reducing liquid sample volume using centrifugal force

Source: United States Patent and Trademark Office (USPTO). Credit: A. Menarini Industrie Farmaceutiche Riunite Srl

The patent US12005450B2 outlines a method for reducing the volume of a liquid sample, which can include microparticles, using a specialized container. The method involves an acceleration step where a manipulation assembly moves the container, applying an acceleration that directs a portion of the liquid out through an opening while retaining a defined volume within the container. This process utilizes centrifugal force generated by rotating the container around a specific axis, ensuring that the liquid flows out while leaving behind a second part of the sample. The claims also detail the application of inertial forces during this step, which are designed to exceed or remain below certain retaining forces to facilitate the separation of the sample components.

Additionally, the method includes various preparatory and treatment steps, such as pre-treatment to position microparticles, insertion of the sample, and treatment with reactants or washing liquids. The claims specify that the manipulation assembly can handle multiple containers simultaneously and may incorporate features like a collecting device to capture the expelled liquid. Furthermore, the method allows for the application of magnetic forces to assist in retaining or removing specific materials during the acceleration step. The patent emphasizes the versatility of the method, which can be applied to a range of microparticles, including cells and other biological materials, while maintaining controlled conditions such as temperature throughout the process.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies