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In Brief
Spotlight

GLP-1RA non-responders: tackling a hidden challenge behind the obesity epidemic 

Improving outcomes for patients classed as ‘non-responders’ remains a key unmet need within the obesity space.

Latest news

FDA approves expanded indication for Lilly’s Jaypirca

The regulatory decision is supported by data from the primary analysis of the Phase III BRUIN CLL-313 clinical study.

Bayer plans $2.2bn pharmaceutical manufacturing facility in Ohio, US

The investment adds to more than $7bn spent by Bayer on research, development, and manufacturing in the US.

AstraZeneca deepens Summit ties on ADC-bispecific cancer combo testing pact 

Ivonescimab is currently in development as a combination drug across several types of solid tumours.

Novartis bets on autoimmune BiTEs through $7.8bn Abogen deal 

Unlike other therapies in this class, Abogen’s ABO2203 is designed to produce a T-cell engager protein in vivo through an mRNA-encoded system.

Magazine: Keep it cool

In this issue: Key themes of CPHI 2026, the GLP-1 manufacturing shift, cold chain logistics, and more.