Italy has accounted for a 3.3% share of the global clinical trials activity in 2020, registering a decrease when compared with the last ten-year average of a 4.8% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials in Italy

Industry sponsored trials held a 75.9% share of all the clinical trials in Italy in 2020, when compared with the ten-year average of 73.7%. Non-industry sponsored trials accounted for a 24.1% share in 2020 as against the average of 26.3% in the last ten years.

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Top therapy areas for industry sponsored clinical trials in Italy

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Oncology was the leading therapy area for industry sponsored clinical trials in Italy in 2020 with a 37.9% share, as against a five-year average of 40.3% and a ten-year average of 38.9%.

Infectious Disease held a 14.9% share in 2020, over a five-year average of 5.7% and a ten-year average of 7.6%.

Central Nervous System held a 10.6% share in 2020, compared to a five-year average of 11.6% and a ten-year average of 11.7%. Respiratory held an 8.6% share in 2020, as against a five-year average of 4.6% and a ten-year average of 4.8%.

Hematological Disorders held a 7.4% share, over a five-year average of 5.6% and a ten-year average of 5.4%.

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Top therapy areas for non-industry sponsored clinical trials in Italy

Infectious Disease was the leading therapy area for non-industry sponsored clinical trials in Italy in 2020 with a 37.3% share, as against a five-year average of 7.3% and a ten-year average of 7.4%.

Oncology held a 24.9% share in 2020, over a five-year average of 26.7% and a ten-year average of 28.5%.

Respiratory held a 23.7% share in 2020, compared to a five-year average of 3.3% and a ten-year average of 3.9%. Cardiovascular held an 11.9% share in 2020, as against a five-year average of 14.5% and a ten-year average of 15.2%.

Central Nervous System held an 11.9% share, over a five-year average of 18.6% and a ten-year average of 16.7%.

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Phase III trials lead industry sponsored clinical trials in Italy in 2020

Phase III trials held a 50.2% share of industry sponsored clinical trials in Italy in 2020, over a five-year average of 47.9% and a ten-year average of 47.7%.

Phase II trials held a 36.5% share in 2020, as against a five-year average of 37.4% and a ten-year average of 36.5%. Phase IV trials held an 8.1% share in 2020, compared to a five-year average of 9.9% and a ten-year average of 11.3%.

Phase I trials held a 5.2% share in 2020, over a five-year average of 4.8% and a ten-year average of 4.5%.

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Phase II trials lead non-industry sponsored clinical trials in Italy in 2020

Phase II trials held a 54.2% share of non-industry sponsored clinical trials in Italy in 2020, over a five-year average of 58.1% and a ten-year average of 52.6%.

Phase III trials held a 23.2% share in 2020, as against a five-year average of 12.5% and a ten-year average of 15.6%. Phase IV trials held a 20.3% share, compared to a five-year average of 27.8% and a ten-year average of 29.9%.

Phase I held a 2.3% share in 2020, over a five-year average of 1.6% and a ten-year average of 1.9%.

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Methodology:

The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.