Fosfomycin + metronidazole is under clinical development by Reponex Pharmaceuticals and currently in Phase II for Colon Cancer. According to GlobalData, Phase II drugs for Colon Cancer have an 11% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Fosfomycin + metronidazole’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Fosfomycin + metronidazole overview
RNX-051 is under development for colon adenoma and colorectal cancer. It is a combination of fosfomycin and metronidazole. Fosfomycin acts by targeting uridine diphosphate-GlcNAc enol-pyruvyltransferase (MurA) enzyme and metronidazole is a synthetic nitroimidazole derivative that acts by targeting DNA synthesis.
It was also under development for bacterial infections.
Reponex Pharmaceuticals overview
Reponex Pharmaceuticals, a subsidiary of Pharma Equity Group A/S is a biopharmaceutical company. It offers pharmaceuticals and therapies for chronic diseases. Reponex Pharmaceuticals drug candidates include RNX-011, RNX-021, RNX-022, RNX-023, RNX-041 and RNX-051. It develops new, effective treatments for acute or life threatening disease, such as bacterial peritonitis and colorectal cancer, or may be chronic diseases that reduce lifespan and the quality of life. The company also provides drug administration platform for local targeted treatments. Reponex Pharmaceuticals is headquartered in Horsholm, Denmark.
For a complete picture of Fosfomycin + metronidazole’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
