TX-000045 is under clinical development by Tectonic Therapeutic Inc and currently in Phase II for Congestive Heart Failure (Heart Failure). According to GlobalData, Phase II drugs for Congestive Heart Failure (Heart Failure) have a 46% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how TX-000045’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

TX-000045 overview

TX-000045 is under development for the treatment of congestive heart failure and pulmonary hypertension secondary to heart failure with preserved ejection fraction (PH-HFpEF). It acts by targeting relaxin receptor 1 (RXFP1). The drug candidate is administered through intravenous and subcutaneous route. It is being developed based on GEODe platform.

Tectonic Therapeutic Inc overview

Tectonic Therapeutic Inc is a biotechnology company that is engaged in developing therapeutic proteins and antibodies modulate the activity of GPCRs G-protein Coupled Receptors (GPCRs). The company is headquartered in Watertown, Massachusetts, the US.

For a complete picture of TX-000045’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.