PRT-3789 is under clinical development by Prelude Therapeutics and currently in Phase I for Colorectal Cancer. According to GlobalData, Phase I drugs for Colorectal Cancer have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how PRT-3789’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

PRT-3789 overview

PRT-3789 is under development for the treatment of solid tumor non-small cell lung cancer, pancreatic cancer, breast cancer, ovarian cancer, colorectal cancer, cholangiocarcinomac and esophageal cancer. It is administered through intravenous route. It acts by targeting probable global transcription activator SNF2L2 (SMARCA2). It was under development for the treatment of endometrial cancer.

Prelude Therapeutics overview

Prelude Therapeutics (Prelude) is a clinical-stage oncology company that provides drug discovery and development for the treatment of cancers. The company pipeline products include PRT3789, PRT2527 and PRT3645 for the indication including solid Tumors, and Heme Malignancies. Its other pipelines include pipeline includes an IV-administered, potent and highly selective SMARCA2 degrader, PRT3789, a preclinical oral SMARCA2 selective degrader, PRT7732, a potent and highly selective CDK9 inhibitor, PRT2527, and a next-generation CDK4/6 inhibitor, PRT3645. The company collaborates with AbCellera Biologics. on an early-stage discovery program. Prelude is headquartered in Wilmington, Delaware, the US.

For a complete picture of PRT-3789’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.