ZM-008 is under clinical development by Zumutor Biologics and currently in Phase I for Non-Small Cell Lung Cancer. According to GlobalData, Phase I drugs for Non-Small Cell Lung Cancer have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ZM-008’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ZM-008 overview

ZM-008 is under development for the treatment of unspecified B cell lymphoma, glioblastoma multiforme, prostate cancer, non-small cell lung cancer (NSCLC), triple-negative breast cancer (TNBC), head and neck squamous cell carcinoma (HNSCC), colorectal cancer (CRC), pancreatic ductal adenocarcinoma (PDAC), biliary tract cancer, high grade serious ovarian cancer, diffuse large B-cell lymphoma and urothelial cancer. The drug candidate is administered through intravenous route. The drug candidate acts by targeting lectin like transcript 1.

It was also under development for the treatment of rheumatoid arthritis.

Zumutor Biologics overview

Zumutor Biologics is developing first-in-class therapeutic antibodies which target innate immunity and regulate the tumor microenvironment. The company is headquartered in Cambridge, Massachusetts, the US.

For a complete picture of ZM-008’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 12 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.