Ibezapolstat is a small molecule commercialized by Acurx Pharmaceuticals, with a leading Phase II program in Clostridioides difficile Infections (Clostridium difficile Associated Disease). According to Globaldata, it is involved in 4 clinical trials, of which 2 were completed, and 2 are planned. GlobalData uses proprietary data and analytics to provide a complete picture of Ibezapolstat’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for Ibezapolstat is expected to reach an annual total of $60 mn by 2036 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Ibezapolstat Overview
Ibezapolstat (ACX-362E) is under development for the treatment of Clostridium difficile Infections. The drug candidate is administered through oral route in the form of capsules. It acts by targeting DNA polymerase IIIc. Th drug candidate is an analog of 2-deoxyguanosine 5-triphosphate (dGTP).
Acurx Pharmaceuticals Overview
Acurx Pharmaceuticals, LLC, (formerly Ampex Pharmaceuticals), a biopharmaceutical company that focused on developing new antibiotics for difficult to treat infections. The company is headquartered in United States.
The operating loss of the company was US$14.6 million in FY2023, compared to an operating loss of US$12.1 million in FY2022. The net loss of the company was US$14.6 million in FY2023, compared to a net loss of US$12.1 million in FY2022.
For a complete picture of Ibezapolstat’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
