Aquestive Therapeutics. has been granted a patent for a pharmaceutical composition that features a polymeric matrix designed to enhance the permeation of active components, specifically including epinephrine or its acceptable salts or esters, along with an adrenergic receptor interactor. GlobalData’s report on Aquestive Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Aquestive Therapeutics, Nanoparticle drug conjugates was a key innovation area identified from patents. Aquestive Therapeutics's grant share as of July 2024 was 30%. Grant share is based on the ratio of number of grants to total number of patents.

Enhanced pharmaceutical compositions for active component permeation

Source: United States Patent and Trademark Office (USPTO). Credit: Aquestive Therapeutics Inc

The granted patent US12023309B2 outlines a pharmaceutical composition that integrates a polymeric matrix with a pharmaceutically active component, specifically epinephrine or its acceptable salts or esters, alongside an adrenergic receptor interacter. The claims detail various forms of the adrenergic receptor interacter, including natural compounds such as farnesol, linoleic acid, and eugenol, as well as synthetic or biosynthetic phytoextracts derived from clove plants. The composition can be formulated in multiple dosage forms, including chewable tablets, gels, creams, and films, and may incorporate a variety of polymeric materials, such as mucoadhesive polymers, cellulosic polymers, and polyethylene oxide.

Additionally, the patent describes methods for creating the pharmaceutical composition by combining the adrenergic receptor interacter with the active component within the polymeric matrix. The claims also encompass the inclusion of stabilizers and other excipients to enhance the formulation's efficacy and stability. Notably, the composition can be designed to contain the active components in discrete layers, allowing for controlled release. The patent further specifies a device that can dispense the pharmaceutical composition, indicating potential applications in delivering the formulation effectively to patients.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies