Melinta Therapeutics has been granted a patent for a method to treat Acute Bacterial Skin and Skin Structure Infections (ABSSSI) in overweight or obese patients. The method involves administering 300 mg of delafloxacin intravenously twice daily. GlobalData’s report on Melinta Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Melinta Therapeutics, NSAID cancer drugs was a key innovation area identified from patents. Melinta Therapeutics's grant share as of July 2024 was 41%. Grant share is based on the ratio of number of grants to total number of patents.

Treating infections in obese patients with delafloxacin

Source: United States Patent and Trademark Office (USPTO). Credit: Melinta Therapeutics LLC

The granted patent US12036219B2 outlines a specific method for treating Acute Bacterial Skin and Skin Structure Infections (ABSSSI) in overweight or obese patients. The method involves the intravenous administration of 300 mg of delafloxacin, or its pharmaceutically acceptable salt, ester, or prodrug, twice daily. This treatment is particularly targeted at patients who are classified as overweight or obese, defined by a body mass index (BMI) of 25 or higher.

The claims further specify various BMI thresholds for the patient population, detailing that the method is applicable to individuals with a BMI of 30 or greater, 35 or greater, and 40 or greater. This stratification indicates a focus on progressively higher levels of obesity, suggesting that the treatment may be tailored to address the unique needs of patients within these specific BMI categories. The patent emphasizes the importance of this method in effectively managing ABSSSI in a demographic that may face increased health risks due to their weight status.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies