Omeros has been granted a patent for compounds that inhibit MASP-2 activity. The patent includes compositions of these compounds and outlines methods for their production and use, with a specific structural claim for one of the compounds. GlobalData’s report on Omeros gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Omeros, Peptide pharmacophores was a key innovation area identified from patents. Omeros's grant share as of July 2024 was 45%. Grant share is based on the ratio of number of grants to total number of patents.
The granted patent US12030853B2 outlines a novel compound characterized by a specific structural formula, referred to as Structure (I). The claims detail various configurations of this compound, emphasizing the versatility of substituents represented by R1, R2a, R2b, R2c, R2d, R3, and R4. Notably, R1 can be selected from pyridinyl, pyrrolopyridinyl, or benzoimidazolyl groups. The claims further specify that at least one of the substituents R2a to R2d may include a range of functional groups such as alkoxy, cyano, halo, and various carbonyl derivatives, allowing for significant structural diversity. The variable n can take values of 0, 1, or 2, with specific claims detailing configurations when n equals 2, particularly when R4 is an aryl or heteroaryl group.
Additionally, the patent encompasses pharmaceutical compositions that incorporate the claimed compound or its derivatives, including stereoisomers, tautomers, or pharmaceutically acceptable salts, combined with suitable carriers or excipients. This broad scope suggests potential applications in therapeutic formulations, leveraging the structural variations of the compound to enhance efficacy or target specific biological pathways. The detailed claims provide a comprehensive framework for understanding the compound's chemical properties and potential uses in pharmaceutical development.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
