The Transcription Activator BRG1 pipeline drugs market research report outlays comprehensive information on the Transcription Activator BRG1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Transcription Activator BRG1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology which include the indications Prostate Cancer, and Solid Tumor. It also reviews key players involved in Transcription Activator BRG1 targeted therapeutics development with respective active and dormant or discontinued products.
The Transcription Activator BRG1 pipeline targets constitutes close to seven molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 1, 3, and 2 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Transcription Activator BRG1 overview
The Transcription Activator BRG1, also known as SMARCA4, is a pivotal component of the SWI/SNF chromatin remodeling complex, which plays a fundamental role in regulating gene expression by modulating chromatin structure. As a catalytic subunit of this complex, BRG1 utilizes the energy from ATP hydrolysis to alter the positioning of nucleosomes, facilitating access to DNA by transcriptional machinery. BRG1 is implicated in diverse cellular processes, including embryonic development, cell cycle control, and DNA repair. It acts as a transcriptional activator by promoting the expression of genes involved in these critical cellular functions. Moreover, BRG1 is frequently found to be mutated or dysregulated in various cancers, highlighting its significance in tumorigenesis and tumor progression.
For a complete picture of Transcription Activator BRG1’s drug pipeline, buy the report here.
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