The Cyclin Dependent Kinase 9 pipeline drugs market research report outlays comprehensive information on the Cyclin Dependent Kinase 9 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Cyclin Dependent Kinase 9 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Infectious Disease, Respiratory, and Immunology which include the indications Solid Tumor, Breast Cancer, Human Immunodeficiency Virus (HIV) Infections (AIDS), Epstein–Barr Virus (HHV-4) Infections, Idiopathic Pulmonary Fibrosis, and Rheumatoid Arthritis. It also reviews key players involved in Cyclin Dependent Kinase 9 targeted therapeutics development with respective active and dormant or discontinued products.
The Cyclin Dependent Kinase 9 pipeline targets constitutes close to 31 molecules. Out of which, approximately 25 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase II, Phase I, Preclinical, and Discovery stages are 1, 9, 4, 9, and 2 respectively. Similarly, the universities portfolio in Phase I, Preclinical, and Discovery comprises 1, 3, and 2 molecule.
Cyclin Dependent Kinase 9 overview
Cyclin-dependent kinase 9 (CDK9) is a cyclin-dependent kinase associated with P-TEFb. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with CDK9 and cyclin T, which suggested a possible involvement of this protein in AIDS.
For a complete picture of Cyclin Dependent Kinase 9’s drug pipeline, buy the report here.
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