Stealth BioTherapeutics has been granted a patent for methods involving administering aromatic-cationic peptides to treat or prevent hyperalgesia caused by drug-induced neuropathy. The patent also includes a claim for increasing chemotherapeutic agent doses by administering a specific peptide to prevent neuropathic conditions. GlobalData’s report on Stealth BioTherapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Stealth BioTherapeutics, was a key innovation area identified from patents. Stealth BioTherapeutics's grant share as of May 2024 was 16%. Grant share is based on the ratio of number of grants to total number of patents.
Treating or preventing drug-induced neuropathy to increase chemotherapy dose
A recently granted patent (Publication Number: US11998585B2) discloses a method for increasing the dose of a chemotherapeutic agent in patients by administering a specific peptide or its salt. The peptide, Phe-D-Arg-Phe-Lys-NH2, effectively treats or prevents neuropathic conditions induced by the chemotherapeutic agent, allowing for a higher dose to be administered.
The method outlined in the patent targets dose-limiting neuropathic conditions such as myalgia, painful burning paresthesia, glove-and-stocking sensory neuropathy, hyperalgia, and allodynia. Administering the peptide, either prior to or simultaneously with the chemotherapeutic agent, has shown promise in managing these conditions, particularly in cases where vincristine is the chemotherapeutic agent used. The patent provides a novel approach to potentially enhance the efficacy of chemotherapy while managing associated neuropathic side effects.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
