SOM-401 is under clinical development by Inflammasome Therapeutics and currently in Phase I for Geographic Atrophy. According to GlobalData, Phase I drugs for Geographic Atrophy have a 92% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how SOM-401’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
SOM-401 overview
SOM-401 (kamuvudine-8, K8) is under development for the treatment of diabetic macular edema, geographic atrophy (GA) due to age-related macular degeneration (AMD). It is administered through intravitreal route as implant. The drug candidate is a chemical derivative of nucleoside reverse transcriptase inhibitor (NRTI), which is derived from zidovudine.
Inflammasome Therapeutics overview
Inflammasome Therapeutics is developing medicines for prevalent, degenerative diseases including Alzheimer’s disease, multiple sclerosis, Parkinson’s disease and macular degeneration. The company is headquartered in Newton, Massachusetts, the US.
For a complete picture of SOM-401’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
